How To Store And Preserve FFPE Tissue Blocks

FFPE tissue blocks are high-quality and demand a premium rate for their use in research. These pieces of tissue are used for things such as DNA, RNA, and other genetic tests. But when it comes to storing these samples, the use of conventional methods can lead to damage that is irreversible. Find out how to preserve these samples without damaging them!

FFPE tissue is the pathological tissue left out of a surgical specimen. This tissue can either be in form of blocks, pellets, or sheets. FFPE tissues are removed during surgery and then put back into storage until they are needed. FPTE tissue is the same as FFPE tissue but it has been frozen and stored on dry ice. This preserves the ffpe block storage for future use.

 ffpe block storage

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What are the advantages of FFPE tissues? 

Some of the advantages of FFPE tissues are:

  • The tissues can be used for acute studies and to research diseases or conditions.
  • The tissues can be used for immunohistochemistry (IHC).
  • Can be used for histopathology (histological analysis)
  • FFPE tissues are used for transplantation. 
  • Can be used in the production of recombinant proteins.
  • It has a long-term storage life.
  • Unfolds better than FFPE tissue on staining procedures.

If you have a lab that is storing FFPE tissue blocks, it is important to know how to store these tissue blocks safely. There are many things that can happen to tissue during storage, and these will lead to an adverse effect on the quality of the tissue. One way to store these tissue blocks without any problems is in small vials at or below -80 degrees Celsius with tight-fitting covers. It is also important to use these vials with nitrogen gas flow in order to avoid contamination and ensure safety and sterility.